Volume 28, Issue 50
Natural Products
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ChemInform Abstract: Synthesis of the Marine Dibromooxoindoline Convolutamydine C.

S. MIAH

S. MIAH

Dep. Chem., Univ. Exeter, Exeter, Devon EX4 4QD, UK

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C. J. MOODY

C. J. MOODY

Dep. Chem., Univ. Exeter, Exeter, Devon EX4 4QD, UK

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I. C. RICHARDS

I. C. RICHARDS

Dep. Chem., Univ. Exeter, Exeter, Devon EX4 4QD, UK

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A. M. Z. SLAWIN

A. M. Z. SLAWIN

Dep. Chem., Univ. Exeter, Exeter, Devon EX4 4QD, UK

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First published: 02 August 2010

Abstract

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ChemInform Abstract

The first synthesis of convolutamydine C (XIII) is described. Key steps are the Rh(II) perfluorobutyramide catalyzed cyclization of diazoamide (V) and the subsequent high yielding one-pot hydrolysis- decarboxylation-oxidation of oxoindoline-3-carboxylate (VIII).

chemical structure image

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