ChemInform Abstract: Synthetic Studies on Indoles and Related Compounds. Part 41. A General Synthetic Route for 1-Substituted 4-Oxygenated β-Carbolines.
Abstract
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ChemInform Abstract
Starting from indole-2-carboxylates the functionalized compounds (VI) are prepared. Their C-3 selective cyclization and functionalization at the C-1 position of the β-carboline nucleus by a modified Reissert-Henze reaction are the key steps in the synthesis to the title compounds (XIII) and (XIV). These compounds can be used as intermediates leading to the general synthesis of this family of compounds.
