Volume 28, Issue 20
Heterocyclic Compounds
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ChemInform Abstract: Synthesis of 3-Fluoro Azetidinone by Electrophilic Fluorination.

J.-P. GENET

J.-P. GENET

Lab. Synth. Org., CNRS, Ec. Natl. Super. Chim., F-75231 Paris, Fr.

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J.-O. DURAND

J.-O. DURAND

Lab. Synth. Org., CNRS, Ec. Natl. Super. Chim., F-75231 Paris, Fr.

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S. ROLAND

S. ROLAND

Lab. Synth. Org., CNRS, Ec. Natl. Super. Chim., F-75231 Paris, Fr.

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M. SAVIGNAC

M. SAVIGNAC

Lab. Synth. Org., CNRS, Ec. Natl. Super. Chim., F-75231 Paris, Fr.

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F. JUNG

F. JUNG

Lab. Synth. Org., CNRS, Ec. Natl. Super. Chim., F-75231 Paris, Fr.

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First published: 04 August 2010

Abstract

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ChemInform Abstract

The title compound (V) is obtained stereoselectively under mild conditions and in good yield as potential intermediate for the synthesis of new antibiotics. It is noteworthy that fluoropyridinium triflates and Barnette′s N-fluorosulfonamide are inefficient for the fluorination of compound (IV).

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