Volume 28, Issue 20
Preparative Organic Chemistry
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ChemInform Abstract: Chemoselective Inhibition of the Hydrogenolysis of the MPM Protective Group for Phenolic Hydroxy Functions Using a Pd/C-pyridine Catalyst.

H. SAJIKI

H. SAJIKI

Lab. Med. Chem., Gifu Pharm. Univ., Mitahora, Gifu 502, Japan

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H. KUNO

H. KUNO

Lab. Med. Chem., Gifu Pharm. Univ., Mitahora, Gifu 502, Japan

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K. HIROTA

K. HIROTA

Lab. Med. Chem., Gifu Pharm. Univ., Mitahora, Gifu 502, Japan

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First published: 04 August 2010

Abstract

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ChemInform Abstract

Employment of a Pd/C-pyridine combination allows the removal of O- benzyl, Cbz and benzyl ester protecting groups and the selective reduction of nitro and olefin functionalities in the presence of phenols protected with the Mpm group.

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