Volume 28, Issue 15
Preparative Organic Chemistry
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ChemInform Abstract: Highly Efficient Enzymatic Resolution of Homoallyl Alcohols Leading to a Simple Synthesis of Optically Pure Fluoxetine and Related Compounds.

H. E. MASTER

H. E. MASTER

Lupin Lab., Ltd., Mandideep 462 046, India

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R. V. NEWADKAR

R. V. NEWADKAR

Lupin Lab., Ltd., Mandideep 462 046, India

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R. A. RANE

R. A. RANE

Lupin Lab., Ltd., Mandideep 462 046, India

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A. KUMAR

A. KUMAR

Lupin Lab., Ltd., Mandideep 462 046, India

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First published: 04 August 2010

Abstract

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ChemInform Abstract

A practical method for the enzymatic resolution of homoallyl alcohols ( I) and its utility for the synthesis of optically pure fluoxetine (V) and related compounds is reported.

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