Volume 27, Issue 23
Natural Products
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ChemInform Abstract: Ring Expansion of Fused Cyclopropylketones. Synthesis of a 12(13 . fwdarw. 18)-abeo-Pregnane.

A. FERRARA

A. FERRARA

Dep. Quim. Org., Fac. Cienc. Exactas Nat., Univ. Buenos Aires, 1428 Buenos Aires, Argent.

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G. BURTON

G. BURTON

Dep. Quim. Org., Fac. Cienc. Exactas Nat., Univ. Buenos Aires, 1428 Buenos Aires, Argent.

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First published: June 4, 1996

Abstract

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ChemInform Abstract

The key step in the synthesis of the steroid hormone analogue (V) is the ring expansion of the cyclopropylketone (IV) using a base-mediated ionic rearrangement.

chemical structure image

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