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ChemInform Abstract: Synthesis of a 1β-Fluorocarbapenem Derivative.
First published: April 30, 1996
Abstract
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ChemInform Abstract
The synthesis of the 1β-fluorocarbapenem derivative (X) starting from the commercially available azetidinone (I) via carbapenem skeleton formation from oxalimide (VII) is given. Attempts to deblock the p-nitrobenzyl ester in (X) fail and result only in the formation of pyrrole derivative (XI) under a variety of conditions.
