ChemInform Abstract: An Approach to Pancratistatin from myo-Inositol.
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract
For the synthesis of 7-deoxypancratistatin a highly advanced synthon ( X) is obtained from the myo-inositol derivative (I). The key step in this approach is the intramolecular cyclization of an intermediately formed arylanion from (VII) to the ring system (VIII). This synthetic strategy might be of more general interest for the synthesis of analogues or for optically active material starting with chiral myo- inositol derivatives.
