ChemInform Abstract: Preparation of (R)-(-)-6,6′-Bis(3,5-dinitrobenzamido)biphenyl-2,2′- dicarboxylic Acid, a Potential Chiral HPLC Selector.
Abstract
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ChemInform Abstract
The synthesis and absolute configuration of optically active diamide ( VI) derived from 6,6′-diaminobiphenyl-2,2′-dicarboxylic acid (I) is reported. This selector combines the features of the C2-symmetrical biphenyl skeleton with those of the polar 3,5-dinitrobenzamide moiety, the almost indispensable component of many effective polar, chiral stationary phases.