Volume 27, Issue 16
Natural Products
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ChemInform Abstract: Synthesis of 2-Alkyl-3-hydroxy-4-pyridinone-ribonucleosides, Potential Oral Iron Chelators.

G. LIU

G. LIU

Div. Radiobiol., Sch. Med., Univ. Utah, Salt Lake City, UT 84112, USA

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F. W. BRUENGER

F. W. BRUENGER

Div. Radiobiol., Sch. Med., Univ. Utah, Salt Lake City, UT 84112, USA

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A. M. BARRIOS

A. M. BARRIOS

Div. Radiobiol., Sch. Med., Univ. Utah, Salt Lake City, UT 84112, USA

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S. C. MILLER

S. C. MILLER

Div. Radiobiol., Sch. Med., Univ. Utah, Salt Lake City, UT 84112, USA

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First published: April 16, 1996

Abstract

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ChemInform Abstract

A simple and useful method for the preparation of sugar derivatives of hydroxylpyridinones (cf. (IV)) is given. These compounds are useful for the removal of iron from overloaded biosystems.

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