Preparative Organic Chemistry
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ChemInform Abstract: Convenient Synthesis of Monoprotected 1,2-Diols.
First published: April 16, 1996
Abstract
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ChemInform Abstract
Ring opening of protected glycidol derivatives (I) by CuCN-catalyzed reaction with Grignard reagents provides the corresponding monoprotected diol derivatives (III) in a highly regioselective fashion under optimal conditions (24 examples).
