Preparative Organic Chemistry
Full Access
ChemInform Abstract: Methyl Carboxymethylenation of Alcohols via Dehydrative Alkylation.
First published: April 16, 1996
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract
A variety of functionalized alcohols undergoes a dehydrative alkylation reaction in a simple, efficient and stereocontrolled manner with methyl phenylsulfonylacetate (II) under modified Mitsunobu conditions to form the adducts shown. A Mg-mediated desulfonylation of some of the products leads to two-carbon elongated methyl carboxylates.
