ChemInform Abstract: Phosphorylation of 1,3-Di(N-alkyl)Azoles by Phosphorus(V) Acid Chlorides - A Route to Potential Haptens Derived from Phosphinic Acids.
Abstract
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ChemInform Abstract
Phosphorylation of imidazoles like (I) and (X) by the chlorides (II) followed by amination or hydrolysis leads to phosphinic (phosphonic) amides, acids or their salts. These compounds, especially functionalized derivatives like (IX) and (XI), are useful precursors of haptens such as (XIV).