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ChemInform Abstract: Total Synthesis of Thymine Polyoxin C.
First published: May 9, 1995
Abstract
ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
ChemInform Abstract
Stereocontrolled addition of 2-lithiofuran (III), a masked carboxylate group, to the N-benzyl nitrone derived from the ribofuranoside (I) is the key step in an expeditious total synthesis of the title compound ( XII). Polyoxins are potent competitive inhibitors of Candiada albicans chitin synthetase.
