ChemInform Abstract: Efficient Cleavage of the Terminal Acetonide Group: Chirospecific Synthesis of 2,5-Dideoxy-2,5-imino-D-mannitol.
Abstract
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ChemInform Abstract
A facile and efficient ion-exchange procedure to cleave selectively primary-secondary acetonide groups is described. This strategy is applied to a convenient synthesis of 2,5-dideoxy-2,5-imino-D-mannitol ( DMDP) (XI).