Volume 25, Issue 40
Heterocyclic Compounds
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ChemInform Abstract: Synthesis of Thieno(3,2-d)- and -(3,4-d)pyrimidines by Alternative Ring Closure Reactions.

D. BRIEL

D. BRIEL

Lehrstuhl Pharm. Chem., Univ., 04103 Leipzig, Germany

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T. MASCHKE

T. MASCHKE

Lehrstuhl Pharm. Chem., Univ., 04103 Leipzig, Germany

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G. WAGNER

G. WAGNER

Lehrstuhl Pharm. Chem., Univ., 04103 Leipzig, Germany

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First published: October 4, 1994

Abstract

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ChemInform Abstract

While treatment of the thiopene (III) with primary amines such as (IV) leads to the formation of the thieno(3,2-d)pyrimidines (V), with ammonia the thieno(3,4-d)pyrimidines (VI) are obtained. Some of the compounds synthesized show antiallergic effects.

chemical structure image

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