Volume 24, Issue 4
Natural Products
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ChemInform Abstract: Synthesis of 5-Homologous AZT and D4T Derivatives.

U. KJAERSGAARD

U. KJAERSGAARD

Dep. Chem., Odense Univ., DK-5230 Odense M, Den.

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E. B. PEDERSEN

E. B. PEDERSEN

Dep. Chem., Odense Univ., DK-5230 Odense M, Den.

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C. NIELSEN

C. NIELSEN

Dep. Chem., Odense Univ., DK-5230 Odense M, Den.

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A. M. EL-TORGOMAN

A. M. EL-TORGOMAN

Dep. Chem., Odense Univ., DK-5230 Odense M, Den.

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First published: January 26, 1993

Abstract

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ChemInform Abstract

5-Alkylhomologues such as (V) and (VI) of 3′-azido-3′-deoxythymidine ( AZT) and 2′,3′-didehydro-3′-deoxythymidine (D4T) are prepared in a search for therapeutic compounds with activity against HIV.

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