ChemInform Abstract: Formation of 1,2,3,4-Tetrahydro-2-pyridones by Aza-Annulation of Imines with Acrylate Derivatives.
Abstract
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ChemInform Abstract
The cyclohexanonimines (I) react with the acrylic anhydrides (II), generated in situ by coupling of acryloyl chlorides with the corresponding sodium acrylates, to form predominantly octahydroquinolinones the (IV). Treatment of (I) with the acryloyl chlorides (VI) only produces the enamides (III).