Volume 22, Issue 39
Natural Products
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ChemInform Abstract: Electrochemical Oxidation of Proline Derivatives: Total Syntheses of Bulgecinine and Bulgecin C.

A. G. M. BARRETT

A. G. M. BARRETT

Dep. Chem., Colorado State Univ., Fort Collins, CO 80523, USA

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D. PILIPAUSKAS

D. PILIPAUSKAS

Dep. Chem., Colorado State Univ., Fort Collins, CO 80523, USA

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First published: October 1, 1991

Abstract

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ChemInform Abstract

Proline derivatives such as (I), prepared by common methods, are oxidized electrochemically in methanol (II) to give the methoxy derivatives (III). (IIId) is converted to bulgecinine (IV) and bulgecin C (V) in multi-step syntheses.

chemical structure image

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