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ChemInform Abstract: Synthesis of 2′,3′-Dideoxy-3′-methylene Pyrimidine Nucleosides as Potential anti-AIDS Agents.
First published: October 1, 1991
Abstract
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ChemInform Abstract
The nucleosides (I) are oxidized with the chromium trioxide/pyridine complex to form the keto nucleosides (II) which are olefinated, yielding the methylene analogues (IV). These are further converted to provide the derivatives (V) and (X).
