ChemInform Abstract: A New Method for the Synthesis of Substituted 3,5-Diphenylisoxazoles.
Abstract
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ChemInform Abstract
Reaction of the diarylhydroxy(hydroxylamino)propenes (I) with benzaldehyde (II) does not lead to the formation of nitrones, but gives the adducts (III) instead which undergo base-induced degradation and ring closure, yielding the 3,5-diarylisoxazoles (IV). (Mechanism).