Volume 21, Issue 48
Heterocyclic Compounds
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ChemInform Abstract: Saturated Heterocycles. Part 162. Synthesis and Steric Structures of 3,4-Disubstituted 1,6,7,11b-Tetrahydropyrimido(6,1-a)isoquinolin-2-ones.

F. + FUELOEP

F. + FUELOEP

Inst. Pharm. Chem., Albert Szent-Gyoergyi Med. Univ., H-6701 Szeged, Hung.

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E. SEMEGA

E. SEMEGA

Inst. Pharm. Chem., Albert Szent-Gyoergyi Med. Univ., H-6701 Szeged, Hung.

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G. BERNATH

G. BERNATH

Inst. Pharm. Chem., Albert Szent-Gyoergyi Med. Univ., H-6701 Szeged, Hung.

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P. SOHAR

P. SOHAR

Inst. Pharm. Chem., Albert Szent-Gyoergyi Med. Univ., H-6701 Szeged, Hung.

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First published: November 27, 1990

Abstract

The reaction of the readily available hydrazide (I) with aldehydes (II) yields hydrazones (III) or heterotricycles (IV) depending upon the proportions of the reagents used.

ChemInform Abstract

The reaction of the readily available hydrazide (I) with aldehydes (II) yields hydrazones (III) or heterotricycles (IV) depending upon the proportions of the reagents used. The similarly obtained hydrazones (VI) can be transformed to the pyrimidoisoquinolines (VII) with aldehydes such as (IIa). The compound (VIII) is analogously obtained.

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