ChemInform Abstract: Saturated Heterocycles. Part 162. Synthesis and Steric Structures of 3,4-Disubstituted 1,6,7,11b-Tetrahydropyrimido(6,1-a)isoquinolin-2-ones.
Abstract
The reaction of the readily available hydrazide (I) with aldehydes (II) yields hydrazones (III) or heterotricycles (IV) depending upon the proportions of the reagents used.
ChemInform Abstract
The reaction of the readily available hydrazide (I) with aldehydes (II) yields hydrazones (III) or heterotricycles (IV) depending upon the proportions of the reagents used. The similarly obtained hydrazones (VI) can be transformed to the pyrimidoisoquinolines (VII) with aldehydes such as (IIa). The compound (VIII) is analogously obtained.