ChemInform Abstract: Syntheses and Reactions of Cyano-1,3,5-triazines.

ChemInform Abstract

The 6-chloro-1,3,5-triazines (I) react with potassium or cuprous cyanide (II) to form the 6-cyano-1,3,5-triazines (III). Similar treatment of 2,4-dimethoxy-6-chloro-1,3,5-triazine (IV) with potassium cyanide (II), however, gives the trimethylisocyanurate (V) together with the triazine derivatives (VI) and (VII). Treatment of (IIIa) with aniline (VIII) and AlCl₃ leads to the formation of the amidinium salt (IX) which gives the 2-triazinylbenzimidazole derivative (X) upon oxidative cyclization with sodium hypochlorite. Reaction of (IIIa) with sodium azide (XI) produces the tetrazole (XII). Additional reactions are described in the original paper. (Mechanism).