Heterocyclic Compounds
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ChemInform Abstract: Synthesis and Reactivity of 7-Dimethylaminocoumarin-3-isocyanate as a Fluorescent Derivatization Reagent for Alcohols.
First published: September 11, 1990
Abstract
The coumarinyl isocyanate (IV), prepared by reaction of the ester (I) with hydrazine hydrate (II) and subsequent diazotization and Curtius rearrangement of the hydrazide (III), is coupled with fourteen alcohols such as (V) to produce the corresponding urethanes (VI).
ChemInform Abstract
The coumarinyl isocyanate (IV), prepared by reaction of the ester (I) with hydrazine hydrate (II) and subsequent diazotization and Curtius rearrangement of the hydrazide (III), is coupled with fourteen alcohols such as (V) to produce the corresponding urethanes (VI). The isocyanate (IV) is used as fluorescent derivatization reagent for alcohols in HPLC.
