Isocyclic Compounds
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ChemInform Abstract: A Mild Reduction of Azomethines with Zinc Borohydride. Synthetic Application to Tandem Alkylation-Reduction of Nitriles.
First published: September 11, 1990
Abstract
Seven secondary amines such as (II) are prepared by reduction of the corresponding azomethines (I) with zinc borohydride.
ChemInform Abstract
Seven secondary amines such as (II) are prepared by reduction of the corresponding azomethines (I) with zinc borohydride. Addition of the Grignard reagents (IV) to the nitriles (III) and subsequent reduction with zinc borohydride yield the branched primary amines (V) after hydrolysis.
