Volume 21, Issue 37
Preparative Organic Chemistry
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ChemInform Abstract: Copper(II) in Organic Synthesis. Part 8. Enantioselective Michael Reactions with Chiral Copper(II) Complexes as Catalysts.

G. DESIMONI

G. DESIMONI

Dip. Chim. Org., Univ., 27100 Pavia, Italy

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P. QUADRELLI

P. QUADRELLI

Dip. Chim. Org., Univ., 27100 Pavia, Italy

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P. P. RIGHETTI

P. P. RIGHETTI

Dip. Chim. Org., Univ., 27100 Pavia, Italy

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First published: September 11, 1990

Abstract

Using chiral copper(II) complexes with tetradentate ligands as catalyst, enantioselective Michael addition is performed to give the adduct (III) with up to 70% e.e.

ChemInform Abstract

Using chiral copper(II) complexes with tetradentate ligands as catalyst, enantioselective Michael addition is performed to give the adduct (III) with up to 70% e.e. If a comparison is made with the catalysts in the literature, only the Cram's crown ether has a superior activity.

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