ChemInform Abstract: Steroids. Part 24. A Novel Efficient Approach to the Synthesis of 6-Oxo-ethinylestradiol (III) and Its 3-Isopropanesulfonate (V).
Abstract
Since the 6-oxo derivatives of steroids usually elicit stronger and more specific immune responses than the steroid itself, the title compounds allow to develop radioimmunoassays of high specificity for (I) and its sulfonate derivative.
ChemInform Abstract
Since the 6-oxo derivatives of steroids usually elicit stronger and more specific immune responses than the steroid itself, the title compounds allow to develop radioimmunoassays of high specificity for (I) and its sulfonate derivative. Another less convenient four-step synthesis is discussed as well.