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ChemInform Abstract: Practical Synthesis of Deoxymannojirimycin and of (2S,3R,4R,5R)-3,4,5-Trihydroxypipecolic Acid from D-Glucose.
First published: May 30, 1989
Abstract
Deoxymannojirimycin (X) is synthesized as shown in the scheme starting from the glucose derivative (II) which is readily available from diacetone glucose (I).
ChemInform Abstract
Deoxymannojirimycin (X) is synthesized as shown in the scheme starting from the glucose derivative (II) which is readily available from diacetone glucose (I). The overall yield of (X) from (I) amounts to 35%. In addition, the intermediate lactol (VIII) can be converted to the trihydroxypipecolic acid (XI).
