Heterocyclic Compounds
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ChemInform Abstract: Synthesis of Aryl-Substituted Pyridines by Liquid-Phase Condensation of Aldehydes with Urea Catalyzed by Transition Metal Complexes.
First published: May 30, 1989
Abstract
Cocondensation of the (het)aromatic aldehydes (I) with butyraldehyde (II) in the presence of urea (III) and a Co(II)/triethylaluminum catalytic system gives the (het)arylpyridines (IV), together with the diethylpropylpyridine (V).
ChemInform Abstract
Cocondensation of the (het)aromatic aldehydes (I) with butyraldehyde (II) in the presence of urea (III) and a Co(II)/triethylaluminum catalytic system gives the (het)arylpyridines (IV), together with the diethylpropylpyridine (V). Paraldehyde (VI) reacts with (Ia) and (III) under the same conditions to produce the 2,4-diarylpyridine (VII) and the methylethylpyridine (VIII).
