ChemInform Abstract: Total Synthesis of Boromycin.
Abstract
Coupling of the synthons (IV) and (VII) and subsequent work-up affords the boromycin precursor (IXa).
ChemInform Abstract
Coupling of the synthons (IV) and (VII) and subsequent work-up affords the boromycin precursor (IXa). The latter has already been converted to the title compound (IXb) by treatment with Boc-D-Val, followed by TFA. The reaction sequence starting from the lactone (I) constitutes the first total synthesis of boromycin.