Preparative Organic Chemistry
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ChemInform Abstract: An Unusual Ring Reorganization of a N-Styrylisothiazolethione to a 2-Styrylthiazole.
First published: May 2, 1989
Abstract
Sulfurization of the isothiazolone (I) with phosphorus pentasulfide gives the isothiazolethione (II) which rearranges on methylation with trimethyloxonium tetrafluoroborate (III), forming the thiazole (IV).
ChemInform Abstract
Sulfurization of the isothiazolone (I) with phosphorus pentasulfide gives the isothiazolethione (II) which rearranges on methylation with trimethyloxonium tetrafluoroborate (III), forming the thiazole (IV). This is oxidized to give the sulfone (V).
