Heterocyclic Compounds
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ChemInform Abstract: Studies on the Synthesis and Antimicrobial Properties of Aryl Barbituryl Sulfones.
Abstract
The sulfonamides (III) are coupled with the ureas (IV) to give the barbituric acid derivatives (V) which rearrange in concentrated sulfuric acid, producing the corresponding sulfones (VI).
ChemInform Abstract
The sulfonamides (III) are coupled with the ureas (IV) to give the barbituric acid derivatives (V) which rearrange in concentrated sulfuric acid, producing the corresponding sulfones (VI). In general, these sulfones prove to show more antibacterial activity than the corresponding sulfonamides (V).
