Heterocyclic Compounds
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ChemInform Abstract: 2-Benzoyl-4-substituted-phenyl-5-phenylthiazoles.
First published: January 10, 1989
Abstract
The α-bromodeoxybenzoins (I) are cyclized with the thioamide (II) to give the thiazoles (III).
ChemInform Abstract
The α-bromodeoxybenzoins (I) are cyclized with the thioamide (II) to give the thiazoles (III). Hydrolysis of (III) and subsequent oxidation of the carbinols (IV) form the 2-benzoylthiazoles (V) which are of interest because of their expected antibacterial activity and low toxicity. (No yields given).
