Volume 20, Issue 2
Heterocyclic Compounds
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ChemInform Abstract: Cycloaddition of Isopropylidene Methylenemalonate to Isosafrole and Analogues.

R. STEVENSON

R. STEVENSON

Dep. Chem., Brandeis Univ., Waltham, MA 02254, USA

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J. V. WEBER

J. V. WEBER

Dep. Chem., Brandeis Univ., Waltham, MA 02254, USA

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First published: January 10, 1989

Abstract

Isosafrole (I) and the styrenes (V) undergo cycloaddition reaction with isopropylidene methylenemalonate (II) to give the trioxaoctalinones (III) and (VI).

ChemInform Abstract

Isosafrole (I) and the styrenes (V) undergo cycloaddition reaction with isopropylidene methylenemalonate (II) to give the trioxaoctalinones (III) and (VI). Subsequent hydrolysis produces the lactones (IV) and (VII) or the pentenoic acid (VIII). (Yields partly given in g).

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