Heterocyclic Compounds
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ChemInform Abstract: Nucleophilic Displacements of Imidazoles. Part 1. Oxygen, Nitrogen and Carbon Nucleophiles.
First published: January 12, 1988
Abstract
The title reaction of the 5-iodo-imidazoles (I) leads to the products (III), while the compounds (VII) are obtained from analogous reactions of the 4-iodo-imidazoles (VI) and (VIII).
ChemInform Abstract
The title reaction of the 5-iodo-imidazoles (I) leads to the products (III), while the compounds (VII) are obtained from analogous reactions of the 4-iodo-imidazoles (VI) and (VIII). The reaction of the latter with KCN (V) unexpectedly yields the product (IIId), resulting from a methyl migration. The structure of (IIIc) is confirmed by X-ray analysis (space group P21/c with Z=4).
