ChemInform Abstract: Oxygen-Containing Heterocycles. Part 17. Synthesis and Anticonvulsive Activity of Cyclic Imides and Amines from 2-Carboxy-1,3-benzodioxole-2- acetic Acid.
Abstract
Starting with the benzodioxole derivative (I), the spirocyclic imides (VI) and amines (VII) are prepared as shown in the reaction scheme.
ChemInform Abstract
Starting with the benzodioxole derivative (I), the spirocyclic imides (VI) and amines (VII) are prepared as shown in the reaction scheme. The imides (VI) have no anticonvulsive activity, whereas the amines (VII) show selective anticonvulsive action against electric shock.