Natural Products
Full Access
ChemInform Abstract: Use of 2-Methyl-2-propanethiol in the Synthesis of C-Thioglycosyl Derivatives.
First published: June 16, 1987
Abstract
Reaction of (I) with 2-methyl-2-propanethiol in an acidic medium yields a mixture of the diastereomers (II).
ChemInform Abstract
Reaction of (I) with 2-methyl-2-propanethiol in an acidic medium yields a mixture of the diastereomers (II). Prolonged reaction gives the β-thiofuranoside (IV), together with (II) as by-products. In addition to (III), the corresponding α-anomer (V) is obtained by cyclization of the tert-butylthio derivative (IV), prepared from (I) in two steps. (IR-, MS-, 1H-, 13C-NMR-data).
