Simulation of Azelaic Acid Crystallization Process Based on MATLAB and Aspen Plus
Zhiyuan Zhao
School of Chemical Engineering, Hebei University of Technology, No.8 Guangrong Road, Tianjin, 300130 China
National-Local Joint Engineering Laboratory for Energy Conservation of Chemical Process Integration and Resources Utilization, No.8 Guangrong Road, Tianjin, 300130 China
Search for more papers by this authorCorresponding Author
Weiyi Su
School of Chemical Engineering, Hebei University of Technology, No.8 Guangrong Road, Tianjin, 300130 China
National-Local Joint Engineering Laboratory for Energy Conservation of Chemical Process Integration and Resources Utilization, No.8 Guangrong Road, Tianjin, 300130 China
E-mail: [email protected]
Search for more papers by this authorMengyao Wang
School of Chemical Engineering, Hebei University of Technology, No.8 Guangrong Road, Tianjin, 300130 China
National-Local Joint Engineering Laboratory for Energy Conservation of Chemical Process Integration and Resources Utilization, No.8 Guangrong Road, Tianjin, 300130 China
Search for more papers by this authorWenxiu Yang
School of Chemical Engineering, Hebei University of Technology, No.8 Guangrong Road, Tianjin, 300130 China
National-Local Joint Engineering Laboratory for Energy Conservation of Chemical Process Integration and Resources Utilization, No.8 Guangrong Road, Tianjin, 300130 China
Search for more papers by this authorQi Hao
School of Chemical Engineering, Hebei University of Technology, No.8 Guangrong Road, Tianjin, 300130 China
National-Local Joint Engineering Laboratory for Energy Conservation of Chemical Process Integration and Resources Utilization, No.8 Guangrong Road, Tianjin, 300130 China
Search for more papers by this authorXiong Yu
School of Chemical Engineering, Hebei University of Technology, No.8 Guangrong Road, Tianjin, 300130 China
National-Local Joint Engineering Laboratory for Energy Conservation of Chemical Process Integration and Resources Utilization, No.8 Guangrong Road, Tianjin, 300130 China
Search for more papers by this authorHonghai Wang
School of Chemical Engineering, Hebei University of Technology, No.8 Guangrong Road, Tianjin, 300130 China
National-Local Joint Engineering Laboratory for Energy Conservation of Chemical Process Integration and Resources Utilization, No.8 Guangrong Road, Tianjin, 300130 China
Search for more papers by this authorZhiyuan Zhao
School of Chemical Engineering, Hebei University of Technology, No.8 Guangrong Road, Tianjin, 300130 China
National-Local Joint Engineering Laboratory for Energy Conservation of Chemical Process Integration and Resources Utilization, No.8 Guangrong Road, Tianjin, 300130 China
Search for more papers by this authorCorresponding Author
Weiyi Su
School of Chemical Engineering, Hebei University of Technology, No.8 Guangrong Road, Tianjin, 300130 China
National-Local Joint Engineering Laboratory for Energy Conservation of Chemical Process Integration and Resources Utilization, No.8 Guangrong Road, Tianjin, 300130 China
E-mail: [email protected]
Search for more papers by this authorMengyao Wang
School of Chemical Engineering, Hebei University of Technology, No.8 Guangrong Road, Tianjin, 300130 China
National-Local Joint Engineering Laboratory for Energy Conservation of Chemical Process Integration and Resources Utilization, No.8 Guangrong Road, Tianjin, 300130 China
Search for more papers by this authorWenxiu Yang
School of Chemical Engineering, Hebei University of Technology, No.8 Guangrong Road, Tianjin, 300130 China
National-Local Joint Engineering Laboratory for Energy Conservation of Chemical Process Integration and Resources Utilization, No.8 Guangrong Road, Tianjin, 300130 China
Search for more papers by this authorQi Hao
School of Chemical Engineering, Hebei University of Technology, No.8 Guangrong Road, Tianjin, 300130 China
National-Local Joint Engineering Laboratory for Energy Conservation of Chemical Process Integration and Resources Utilization, No.8 Guangrong Road, Tianjin, 300130 China
Search for more papers by this authorXiong Yu
School of Chemical Engineering, Hebei University of Technology, No.8 Guangrong Road, Tianjin, 300130 China
National-Local Joint Engineering Laboratory for Energy Conservation of Chemical Process Integration and Resources Utilization, No.8 Guangrong Road, Tianjin, 300130 China
Search for more papers by this authorHonghai Wang
School of Chemical Engineering, Hebei University of Technology, No.8 Guangrong Road, Tianjin, 300130 China
National-Local Joint Engineering Laboratory for Energy Conservation of Chemical Process Integration and Resources Utilization, No.8 Guangrong Road, Tianjin, 300130 China
Search for more papers by this authorAbstract
This study develops a coupled model using MATLAB and Aspen Plus to simulate the cooling-antisolvent crystallization of azelaic acid. The solubility was measured using the gravimetric method, and a crystallization kinetics model was built with the population balance equation. Kinetic parameters were obtained through experiments and used as inputs for the model. A key feature was the segmental addition of antisolvent in Aspen Plus. To address Aspen Plus limitations in dynamic solubility changes, a MATLAB-based solubility calculator was developed, feeding solubility data back to Aspen Plus. The simulation results were validated by comparing crystal size distribution data, confirming the model's accuracy. This approach provides a reliable tool for optimizing antisolvent crystallization processes.
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