Volume 42, Issue 9 pp. 1757-1763
Research Article

Fabrication of Bone Scaffolds from Cockle Shell Waste

Siti Hajar Saharudin

Siti Hajar Saharudin

Universiti Malaysia Pahang, Faculty of Chemical and Natural Resources Engineering, Lebuhraya Tun Razak, 26300 Gambang, Kuantan, Pahang, Malaysia

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Jun Haslinda Shariffuddin

Corresponding Author

Jun Haslinda Shariffuddin

Universiti Malaysia Pahang, Faculty of Chemical and Natural Resources Engineering, Lebuhraya Tun Razak, 26300 Gambang, Kuantan, Pahang, Malaysia

Universiti Malaysia Pahang, Centre of Excellence for Advanced Research in Fluid Flow, Lebuhraya Tun Razak, 26300 Gambang, Kuantan, Pahang, Malaysia

Correspondence: Jun Haslinda Shariffuddin ([email protected]), Universiti Malaysia Pahang, Faculty of Chemical and Natural Resources Engineering, Lebuhraya Tun Razak, 26300 Gambang, Kuantan, Pahang, Malaysia.Search for more papers by this author
Noor Ida Amalina Ahamad Nordin

Noor Ida Amalina Ahamad Nordin

Universiti Malaysia Pahang, Faculty of Chemical and Natural Resources Engineering, Lebuhraya Tun Razak, 26300 Gambang, Kuantan, Pahang, Malaysia

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First published: 04 April 2019
Citations: 5

Abstract

Bone scaffold is a three-dimensional structure composed of materials that could enhance bone regeneration. Bone scaffolds were prepared using freeze-drying by varying the cockle shell powder concentration where sodium alginate acted as matrix. The scaffolds were then characterized by X-ray diffraction, Fourier transform infrared spectroscopy, scanning electron microscopy, energy-dispersive X-ray spectroscopy, texture analyzer, and liquid displacement method. The bioactivity of the scaffolds was evaluated by immersion into a simulated body fluid solution. Cockle shell powder concentrations affected the bone scaffold characteristics. The increment of the powder concentrations improved the physicochemical properties and bioactivity of the scaffolds.

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