Volume 106, Issue 1 pp. 288-293
EDUCATION

Complete Revascularization of Multiple Coronary CTOs in a Single Session Using Hydrodynamic Contrast Recanalization

Mangesh Kritya

Corresponding Author

Mangesh Kritya

Department of Structural Heart, Houston Methodist Research Institute, Houston, Texas, USA

Correspondence: Mangesh Kritya ([email protected])

Search for more papers by this author
Shariq Shamim

Shariq Shamim

Department of Cardiovascular Disease, St. Louis Heart and Vascular, St. Louis, Missouri, USA

Search for more papers by this author
Vaibhav Sharma

Vaibhav Sharma

Department of Cardiovascular Disease, St. Louis Heart and Vascular, St. Louis, Missouri, USA

Search for more papers by this author
Akshat Sahai

Akshat Sahai

Department of Cardiovascular Disease, St. Louis Heart and Vascular, St. Louis, Missouri, USA

Search for more papers by this author
Thirugnanasambandam Thayumanavan

Thirugnanasambandam Thayumanavan

Department of Cardiovascular Disease, St. Louis Heart and Vascular, St. Louis, Missouri, USA

Search for more papers by this author
Salman A. Arain

Salman A. Arain

Department of Cardiology, McGovern School of Medicine, University of Texas-Houston, Houston, Texas, USA

Search for more papers by this author
First published: 23 April 2025

Mangesh Kritya and Shariq Shamim are co-first authors.

Procedure performed by Shariq Shamim.

ABSTRACT

Background

Percutaneous coronary intervention (PCI) of chronic total occlusions (CTO) is technically more challenging than non-CTO PCI. The development of novel CTO-specific PCI techniques, such as hydrodynamic contrast recanalization (HDR), has led to improved technical success with low complication rates. We present a case of successful single-session PCI of multiple CTOs using HDR in an elderly patient. Our report highlights the feasibility and advantages of single-session complete revascularization in patients with multiple CTOs.

Case Presentation

A 71-year-old woman with multiple comorbidities, including CAD, heart failure with reduced ejection fraction (HFrEF), chronic kidney disease stage 3 (CKD), and lung cancer in remission, was admitted with NYHA class IV symptoms. Coronary angiography revealed CTO of all three major coronary arteries. Given her high surgical risk and frailty, percutaneous revascularization was recommended by the Heart Team. The patient underwent successful HDR-facilitated CTO PCI of the left anterior descending (LAD), left circumflex (LCX), and right coronary arteries (RCA) in a single session. TIMI 3 flow was restored in all three vessels after successful drug-eluting stent (DES) placement. The patient's symptoms markedly improved postprocedure.

Discussion

HDR is a novel CTO crossing technique that uses contrast modulation beyond the boundary of the proximal cap to facilitate the passage of polymer-jacketed wires. Reported advantages of HDR include a faster crossing time and side branch preservation. Using HDR, we recanalized multiple CTOs in an elderly patient in under 3 h, achieving single-session complete revascularization that improved clinical outcomes and minimized repeat procedural risks. This case highlights the potential role of HDR as a safe and efficient adjunct to conventional CTO PCI techniques in achieving optimal outcomes.

Conflicts of Interest

Dr. Arain has received consulting/speaker honoraria from Boston Scientific, Canon USA, and Teleflex. He serves on the advisory board of Boston Scientific. The remaining authors declare no conflicts of interest.

Data Availability Statement

The data that support the findings of this study are available from the corresponding author upon reasonable request.

The full text of this article hosted at iucr.org is unavailable due to technical difficulties.