Volume 86, Issue 4 pp. 626-631
Coronary Artery Disease

Utility of rotational atherectomy and outcomes over an eight-year period

Lachlan T. Couper MBBS

Lachlan T. Couper MBBS

Department of Cardiology, The Alfred Hospital and Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia

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Philippa Loane BMedSci

Philippa Loane BMedSci

Centre of Cardiovascular Research & Education in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia

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Nick Andrianopoulos MBBS, MBiostat

Nick Andrianopoulos MBBS, MBiostat

Centre of Cardiovascular Research & Education in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia

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Angela Brennan RN

Angela Brennan RN

Centre of Cardiovascular Research & Education in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia

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Shane Nanayakkara MBBS

Shane Nanayakkara MBBS

Department of Cardiology, The Alfred Hospital and Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia

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Nitesh Nerlekar MBBS

Nitesh Nerlekar MBBS

Department of Cardiology, The Alfred Hospital and Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia

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Peter Scott MD

Peter Scott MD

Department of Cardiology, Austin Hospital, Melbourne, Victoria, Australia

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Anthony S. Walton FRACP

Anthony S. Walton FRACP

Department of Cardiology, The Alfred Hospital and Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia

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David J. Clark FRACP

David J. Clark FRACP

Department of Cardiology, Austin Hospital, Melbourne, Victoria, Australia

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Stephen J. Duffy PhD

Stephen J. Duffy PhD

Department of Cardiology, The Alfred Hospital and Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia

Centre of Cardiovascular Research & Education in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia

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Andrew E Ajani MD

Andrew E Ajani MD

Centre of Cardiovascular Research & Education in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia

Department of Cardiology, Royal Melbourne Hospital, Melbourne, Victoria, Australia

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Chris Reid PhD

Chris Reid PhD

Centre of Cardiovascular Research & Education in Therapeutics, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria, Australia

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James A. Shaw PhD

Corresponding Author

James A. Shaw PhD

Department of Cardiology, The Alfred Hospital and Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia

Correspondence to: Dr James A. Shaw, Department of Cardiology Alfred Hospital/Baker IDI Heart and Diabetes Institute, Commercial Rd, Melbourne, 3004, Australia. E-mail: [email protected]Search for more papers by this author
on behalf of the Melbourne Interventional Group (MIG) Investigators

on behalf of the Melbourne Interventional Group (MIG) Investigators

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First published: 08 July 2015
Citations: 15

Conflict of interest: Nothing to report.

Abstract

Objectives

To evaluate outcomes of patients undergoing rotational atherectomy (RA) in a multicenter percutaneous coronary intervention (PCI) registry.

Background

RA remains an important technique for plaque modification in PCI, particularly with complex calcification.

Methods

The study population consisted of consecutive patients undergoing PCI in nine major Australian hospitals, who were treated over an 8-year period (June 2004 to June 2012).

Results

Of 16,577 PCI's, 1.0% of patients n = 167 (214 lesions) underwent RA. Patients undergoing RA were more likely to be older (71.0 ± 9.7 vs. 64.4 ±11.9 years, P < 0.01), with greater incidence of diabetes (37.7% vs. 23.8%, P < 0.01) and renal impairment. There was no significant difference in procedural success (94.6% vs. 95.5%, P = 0.57), dissection (6.1% vs. 4.8%, P = 0.39), transient no reflow (4.4% vs. 2.8%, P = 0.23), or persistent no reflow (0% RA vs. 0.7% non-RA, P = 0.23). Those undergoing RA had a low but increased risk of death at 12 months (6.6 vs. 3.6%, P = 0.04). There was no significant difference in 12 month major adverse cardiovascular outcomes (MACE) between groups following adjustment for univariate predictors (OR 1.00, 95%CI; 0.93–1.08). Additionally, there was no significant difference in 30-day MACE (6.0% vs. 5.1%, P = 0.62) or 30-day mortality (2.4% vs. 1.8%, P = 0.54) between groups.

Conclusions

In this large multicenter registry, RA continues to be used to treat complex lesions with low procedural complications and MACE rates. It is essential for interventional cardiologists to maintain skills in RA to enable effective percutaneous treatment of certain complex lesions. © 2015 Wiley Periodicals, Inc.

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