Volume 20, Issue 5 e202300005

Review

The Inhibitory Activity of Natural Products to Xanthine Oxidase

Dr. Shiyang Zhou

Key Laboratory of Carbohydrate Science and Engineering, College of Chemistry, Chongqing Normal University, Chongqing, 401331 China

School of Environmental and Quality Testing, Chongqing Chemical Industry Vocational College, Chongqing, 401228 China

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Prof. Dr. Gangliang Huang,

Corresponding Author

Prof. Dr. Gangliang Huang

[email protected]

orcid.org/0000-0001-8768-9979

Key Laboratory of Carbohydrate Science and Engineering, College of Chemistry, Chongqing Normal University, Chongqing, 401331 China

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Dr. Shiyang Zhou,

Dr. Shiyang Zhou

Key Laboratory of Carbohydrate Science and Engineering, College of Chemistry, Chongqing Normal University, Chongqing, 401331 China

School of Environmental and Quality Testing, Chongqing Chemical Industry Vocational College, Chongqing, 401228 China

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Prof. Dr. Gangliang Huang,

Corresponding Author

Prof. Dr. Gangliang Huang

[email protected]

orcid.org/0000-0001-8768-9979

Key Laboratory of Carbohydrate Science and Engineering, College of Chemistry, Chongqing Normal University, Chongqing, 401331 China

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First published: 17 April 2023

https://doi.org/10.1002/cbdv.202300005

Citations: 5

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Abstract

The natural products have a new chemical structure and biological active diversity, so they are favored by scientific researchers. Gout is a high incidence and high-risk disease, and the current treatments are not satisfactory. Xanthine oxidase (XO) is a key enzyme responsible for the development and progression of various metabolic and oxidative stress-related diseases. Excessive activity of XO leads to elevated serum urate levels, which in turn leads to the development of hyperuricemia. This review mainly introduces the recent progress of the new research on the anti-gout activity of natural products that could provide new treatment methods for gout and information for the discovery and development of new anti-gout drugs.

Graphical Abstract

Conflict of interest

The authors declare no conflict of interest.

References

1L. Chen, H. Yin F, Z. Lan, J. Ethnopharmacol. 2011, 135, 399–405.
10.1016/j.jep.2011.03.033
CAS PubMed Web of Science® Google Scholar
2H. Choi, D. Mount, Ann. Intern. Med. 2005, 143, 499–516.
10.7326/0003-4819-143-7-200510040-00009
CAS PubMed Web of Science® Google Scholar
3L. Chua, N. Latiffff, S. Lee, Food Chem. 2011, 127, 1186–1192.
10.1016/j.foodchem.2011.01.122
CAS PubMed Web of Science® Google Scholar
4T. Inokuchi, Y. Moriwaki, H. Tsutsui, A. Yamamoto, S. Takahashi, Z. Tsutsumi, Cytokine. 2006, 33, 21–27.
10.1016/j.cyto.2005.11.010
CAS PubMed Web of Science® Google Scholar
5E. Karimi, Z. Hawa, A. Sahida, J. Med. Plants Res. 2011, 5, 1200–1206.
CAS Google Scholar
6E. Karimi, Z. Hawa, A. Syahida, BMC Complementary Altern. Med. 2013, 13, 20.
10.1186/1472-6882-13-20
PubMed Web of Science® Google Scholar
7N. Mamat, J. Jamal, I. Jantan, Sains Malays. 2014, 43, 1827–1833.
10.17576/jsm-2014-4312-03
CAS Web of Science® Google Scholar
8A. Mohd, E. Gupta, Y. Loh, Malays. Fam. Physician. 2011, 6, 72–73.
CAS PubMed Google Scholar
9E. Rahmi, J. Jamal, E. Kumolosasi, Pharmacogn. Mag. 2017, 13, S578-S586.
10.4103/pm.pm_35_17
PubMed Web of Science® Google Scholar
10V. Ravichandran, S. Shalini, K. Sundram, Int. J. Pharm. Pharm. Sci. 2010, 2, 18–22.
Google Scholar
11L. Clarson, P. Chandratre, S. Hider, Eur. J. Prev. Cardiol. 2015, 22, 335–343.
10.1177/2047487313514895
CAS PubMed Web of Science® Google Scholar
12M. Hudaib, K. Tawaha, M. Mohammad, Pharmacogn. Mag. 2011, 7, 320–324.
10.4103/0973-1296.90413
PubMed Web of Science® Google Scholar
13P. Robinson, S. Horsburgh, Maturitas. 2014, 78, 245–251.
10.1016/j.maturitas.2014.05.001
PubMed Web of Science® Google Scholar
14E. Sabina, M. Rasool, L. Mathew, Food Chem. Toxicol. 2010, 48, 229–235.
10.1016/j.fct.2009.10.005
CAS PubMed Web of Science® Google Scholar
15Y. Shi, C. Wang, X. Wang, J. Ethnopharmacol. 2012, 143, 869–904.
10.1016/j.jep.2012.08.023
Web of Science® Google Scholar
16E. Smith, D. Hoy, M. Cross, Ann. Rheum. Dis. 2014, 73, 1470–1476.
10.1136/annrheumdis-2013-204647
PubMed Web of Science® Google Scholar
17A. Subramoniam, V. Madhavachandran, A. Gagaprasad, Ann. Phytomedicine 2013, 2, 3–36.
CAS Google Scholar
18H. Teng, L. Chen, Crit. Rev. Food Sci. Nutr. 2018, 59, 2040–2051.
10.1080/10408398.2018.1437023
Web of Science® Google Scholar
19F. Tu, G. Lin, S. Lee, Joint Bone Spine 2015, 82, 45–51.
10.1016/j.jbspin.2014.07.002
PubMed Web of Science® Google Scholar
20W. Jia, B. Tang, P. Wu, Electrochim. Acta. 2018, 260, 92–100.
10.1016/j.electacta.2017.11.047
CAS Web of Science® Google Scholar
21T. Atabaev, Nanomaterials. 2018, 8, 342.
10.3390/nano8050342
PubMed Web of Science® Google Scholar
22M. Kang, Z. Bolormaa, J. Lee, Kor. J. Mycol. 2011, 39, 53–56.
10.4489/KJM.2011.39.1.053
Google Scholar
23M. Umamaheswari, K. AsokKumar, A. Somasundaram, J. Ethnopharmacol. 2007, 109, 547–551.
10.1016/j.jep.2006.08.020
PubMed Web of Science® Google Scholar
24B. Zanabaatar, J. Song, G. SeoS, Kor. J. Mycol. 2010, 38, 85–87.
10.4489/KJM.2010.38.1.085
Google Scholar
25J. In-Taek, H. Se-Hee, S. Ja-Won, Mycobiology. 2014, 42, 296–300.
10.5941/MYCO.2014.42.3.296
PubMed Web of Science® Google Scholar
26L. MacFarlane, S. Kim, Rheum. Dis. Clin. N. Am. 2014, 40, 581–604.
10.1016/j.rdc.2014.07.002
PubMed Web of Science® Google Scholar
27A. Jain, A. Singhai, V. Dixit, Indian J. Pharm. Sci. 2006, 68, 740–743.
10.4103/0250-474X.31006
CAS Google Scholar
28T. Hussain, S. Fareed, H. Siddiqui, Asian Pac. J. Trop. Med. 2012, 2, 129–132.
10.1016/S2222-1808(12)60030-9
CAS Google Scholar
29A. Enomoto, H. Endou, Clin. Exp. Nephrol. 2005, 9, 195–205.
10.1007/s10157-005-0368-5
CAS PubMed Google Scholar
30N. Kapoor, S. Saxena, J. Biotechnol. 2018, 8, 264.
Google Scholar
31N. Dalbeth, L. Stamp, Semin. Dialysis 2007, 20, 391–395.
10.1111/j.1525-139X.2007.00270.x
CAS PubMed Web of Science® Google Scholar
32M. Souza, C. Paula, M. Resende, J. Ethnopharmacol. 2012, 142, 845–850.
10.1016/j.jep.2012.06.012
CAS PubMed Web of Science® Google Scholar
33S. Sonali, S. Pramila, J. Intern. Med. 2019.
Google Scholar
34F. Haidari, S. Kehavarz, M. Rashidi, J. Clin. Biochem. Nutr. 2009, 45, 285–291.
10.3164/jcbn.09-15
PubMed Web of Science® Google Scholar
35P. Eldiza, K. Endang, H. Khairana, Front. Pharmacol. 2020, 11, 289.
10.3389/fphar.2020.00289
PubMed Web of Science® Google Scholar
36L. Ying, H. Qiong, J. Yan, Bioorg. Chem. 2019, 92, 103302.
10.1016/j.bioorg.2019.103302
PubMed Web of Science® Google Scholar
37F. Huang, S. Jiang, Y. Chen, Spectrochim. Acta Part B 2018, 140, 84–88.
10.1016/j.sab.2017.12.010
CAS Web of Science® Google Scholar
38H. Toker, H. Yuce, A. Yildirim, Braz. Oral Res. 2019, 33, e001.
10.1590/1807-3107bor-2019.vol33.0001
PubMed Web of Science® Google Scholar
39L. Tang, Y. Xu, Y. Wei, Mol. Med. 2017, 16, 6928–6933.
CAS Web of Science® Google Scholar
40A. Ismail, A. Salem, M. Eassawy, J. Photochem. Photobiol. B 2016, 161, 91–99.
10.1016/j.jphotobiol.2016.04.031
CAS PubMed Web of Science® Google Scholar
41L. Shaopeng, L. Lanzhou, Y. Han, Mol. Med. Rep. 2019, 20, 4623–4633.
PubMed Web of Science® Google Scholar
42C. Chen, J. Lu, Q. Yao, Med. Sci. Monit. 2016, 22, 2501–2512.
10.12659/MSM.899852
CAS PubMed Web of Science® Google Scholar
43Chinese Pharmacopoeia Committee. Pharmacopoeia of the People's Republic of China. Beijing, Chinese Medical Science and Technology Press, 2010, 292 p.
Google Scholar
44T. Wang, Q. Guo, P. Mao, Biochem. Syst. Ecol. 2014, 55, 79–83.
10.1016/j.bse.2014.02.023
CAS Web of Science® Google Scholar
45J. Yuan, J. Huang, G. Wu, Ind. Crop. Prod. 2015, 74, 192–199.
10.1016/j.indcrop.2015.04.057
CAS Web of Science® Google Scholar
46G. Chen, S. Chen, Y. Xiao, Ind. Crop. Prod. 2018, 111, 430–445.
10.1016/j.indcrop.2017.10.051
CAS Web of Science® Google Scholar
47H. Song, H. Zhang, Y. Fu, J. Chromatogr. B. 2014, 961, 56–61.
10.1016/j.jchromb.2014.05.001
CAS PubMed Web of Science® Google Scholar
48B. Adamcyzk, J. Simon, V. Kitunen, S. Adamcyzk, ChemistryOpen 2017, 6, 610–614.
10.1002/open.201700113
PubMed Web of Science® Google Scholar
49S. Lin, G. Zhang, Y. Liao, J. Pan, Int. J. Biol. Macromol. 2015, 81, 274–282.
10.1016/j.ijbiomac.2015.08.017
CAS PubMed Web of Science® Google Scholar
50L. Qu, J. Ruan, L. Jin, Phytochem. Lett. 2017, 19, 39–45.
10.1016/j.phytol.2016.11.007
CAS Web of Science® Google Scholar
51A. Debebe, B. Chandravanshi, M. Redi-Abshiro, Bull. Chem. Soc. Ethiop. 2016, 30, 27–37.
10.4314/bcse.v30i1.3
CAS Web of Science® Google Scholar
52K. Loh, Y. Chin, I. Safinar, T. Han, Phytochem. Anal. 2021, 5, 1–11.
Google Scholar
53L. Xuan, L. Shuang, M. Da, Bioorg. Med. Chem. 2016, 26, 2874–2879.
10.1016/j.bmcl.2015.11.072
Web of Science® Google Scholar
54L. Dan, W. Dandan, Y. Wei, M. Dali, Bioorg. Med. Chem. 2017, 25, 13728.
Google Scholar
55G. Strobel, J. Fungi 2018, 4, 57.
10.3390/jof4020057
Web of Science® Google Scholar
56N. Kapoor, S. Saxena, Appl. Biochem. Biotechnol. 2014, 173, 1360–1374.
10.1007/s12010-014-0927-x
CAS PubMed Web of Science® Google Scholar
57A. Andolfi, L. Maddau, A. Cimmino, Phytochemistry. 2014, 103, 145–153.
10.1016/j.phytochem.2014.03.016
CAS PubMed Web of Science® Google Scholar
58J. Seco, E. Quinoa, R. Riguera, Chem. Rev. 2012, 112, 4603–4641.
10.1021/cr2003344
CAS PubMed Web of Science® Google Scholar
59A. Cimmino, M. Masi, M. Evidente, J. Pharm. Biomed. Anal. 2017, 144, 59–89.
10.1016/j.jpba.2017.02.037
CAS PubMed Web of Science® Google Scholar
60K. Sanjay, D. Amol, A. Furkan, Bioorg. Chem. 2019, 87, 851–856.
10.1016/j.bioorg.2018.12.008
PubMed Web of Science® Google Scholar
61R. Arimboor, M. Rangan, S. Aravind, J. Ethnopharmacol. 2011, 133, 1117–1120.
10.1016/j.jep.2010.10.027
CAS PubMed Web of Science® Google Scholar
62M. Santiab, M. Zuninic, B. Verac, Eur. J. Med. Chem. 2018, 143, 577–582.
10.1016/j.ejmech.2017.11.071
PubMed Web of Science® Google Scholar
63Y. Wu, Y. Li, X. Wu, Biochem. Syst. Ecol. 2014, 57, 216–220.
10.1016/j.bse.2014.08.022
CAS Web of Science® Google Scholar
64J. Xie, C. Dong, Food Chem. 2015, 186, 97–105.
10.1016/j.foodchem.2014.06.106
CAS PubMed Web of Science® Google Scholar
65Y. Wang, M. Chen, J. Zhang, Planta Med. 2011, 78, 46–51.
10.1055/s-0031-1280128
CAS PubMed Web of Science® Google Scholar
66J. Flemmig, K. Kuchta, J. Arnhold, Phytomedicine. 2011, 17, 561–566.
10.1016/j.phymed.2010.10.021
Web of Science® Google Scholar
67D. Kumar, G. Kaur, A. Negi, Bioorg. Chem. 2014, 57, 57–64.
10.1016/j.bioorg.2014.08.007
CAS PubMed Web of Science® Google Scholar
68C. Spanou, A. Veskoukis, T. Kerasioti, PLoS One 2012, 7, e32214.
10.1371/journal.pone.0032214
CAS PubMed Web of Science® Google Scholar
69J. Zi, A. Xiao, P. Jian, Bioorg. Chem. 2020, 101, 104018.
10.1016/j.bioorg.2020.104018
PubMed Web of Science® Google Scholar
70Q. Chu, S. Zhang, L. Yu, Int. J. Biol. Macromol. 2019, 130, 892–902.
10.1016/j.ijbiomac.2019.03.012
CAS PubMed Web of Science® Google Scholar
71T. Do, A. Truong, T. Pinnock, Chem. Pharm. Bull. 2013, 61, 624–630.
10.1248/cpb.c12-01081
CAS PubMed Web of Science® Google Scholar
72Y. Dong, H. Huang, M. Zhao, J. Funct. Foods. 2016, 24, 26–36.
10.1016/j.jff.2016.03.021
CAS Web of Science® Google Scholar
73S. Honda, Y. Fukuyama, H. Nishiwaki, Free Radical Biol. Med. 2017, 106, 228–235.
10.1016/j.freeradbiomed.2017.02.037
CAS PubMed Web of Science® Google Scholar
74H. Kaneta, M. Koda, S. Saito, Biosci. Biotechnol. Biochem. 2016, 80, 774–778.
10.1080/09168451.2015.1127132
CAS PubMed Web of Science® Google Scholar
75D. Liu, D. Wang, W. Yang, Bioorg. Med. Chem. 2017, 25, 3562–3566.
10.1016/j.bmc.2017.05.010
CAS PubMed Web of Science® Google Scholar
76M. Santi, M. Zunini, B. Vera, Eur. J. Med. Chem. 2018, 143, 577–582.
10.1016/j.ejmech.2017.11.071
CAS PubMed Web of Science® Google Scholar
77Y. Seo, J. Jeon, M. Jeong, J. Nat. Prod. 2018, 81, 1598–1603.
10.1021/acs.jnatprod.8b00182
CAS PubMed Web of Science® Google Scholar
78J. Kim, C. Jin, Biol. Chem. 2019, 83, 107137.
Google Scholar
79N. Pagidipati, C. Hess, R. Clare, Am. Heart J. 2017, 187, 53–61.
10.1016/j.ahj.2017.02.023
CAS PubMed Web of Science® Google Scholar
80S. Li, Y. Tang, C. Liu, Talanta. 2015, 134, 665–673.
10.1016/j.talanta.2014.12.005
CAS PubMed Web of Science® Google Scholar
81S. Liu, J. Xing, Z. Zheng, Anal. Chim. Acta. 2012, 715, 64–70.
10.1016/j.aca.2011.12.003
CAS PubMed Web of Science® Google Scholar
82A. Jordan, U. Gresser, Pharmaceuticals. 2018, 11, 51–70.
10.3390/ph11020051
Web of Science® Google Scholar
83J. Wang, D. Shi, M. Zheng, J. Sep. Sci. 2017, 40, 4160.
10.1002/jssc.201700690
CAS PubMed Web of Science® Google Scholar
84I. Suntar, H. Khan, S. Pate, Oxid. Met. 2018, 2018, 1–12.
Google Scholar
85A. Chanet, D. Milenkovic, C. Manach, J. Agric. Food Chem. 2012, 60, 8809.
10.1021/jf300669s
CAS PubMed Web of Science® Google Scholar
86Y. Dong, H. Huang, M. Zhao, J. Funct. Foods. 2016, 24, 26–36.
10.1016/j.jff.2016.03.021
CAS Web of Science® Google Scholar
87X. Dong, B. Wang, J. Cao, J. Sep. Sci. 2021, 44, 1353–1360.
10.1002/jssc.202000708
CAS PubMed Web of Science® Google Scholar
88N. Akhtar, M. Ali, A. Sarwar, J. Asian Nat. Prod. Res. 2009, 11, 91–95.
10.1080/10286020802514622
CAS PubMed Web of Science® Google Scholar
89O. Devi, K. Rao, A. Bidalia, Eur. J. Med. Plants 2015, 10, 1–9.
10.9734/EJMP/2015/19353
Google Scholar
90G. Kaleeswaran, D.M. Firake, R. Sanjukta, J. Environ. Manage. 2018, 208, 46–55.
10.1016/j.jenvman.2017.12.017
CAS PubMed Web of Science® Google Scholar
91D. Gupta, S. Mandi, Eur. J. Med. Plants 2013, 1, 1–9.
Google Scholar
92C. Henrique, C. Bertanha, T. Alvarenga, J. Liq. Chromatogr. Relat. Technol. 2016, 39, 65–69.
10.1080/10826076.2015.1126728
CAS Web of Science® Google Scholar
93A. Villiger, F. Sala, A. Suter, V. Butterweck, Phytomedicine. 2015, 22, 138–144.
10.1016/j.phymed.2014.11.015
CAS PubMed Web of Science® Google Scholar
94F. Yasmeen, T. Rauf, M. Babar, J. Pharm. Sci. Pharmacol. 2015, 2, 110–118.
10.1166/jpsp.2015.1050
Google Scholar
95N. Ranjana, B. Zulfa, J. Umme, Ethnopharmacol. 2019, 230, 1–8.
10.1016/j.jep.2018.10.018
CAS PubMed Web of Science® Google Scholar
96V. Nguyen, T. Hoang-Dung, D. Tran, Molecules. 2019, 24, 482.
10.3390/molecules24030482
PubMed Web of Science® Google Scholar
97B. Lin, G. Huang, Food Chem. X 2022, 15,100388.
10.1016/j.fochx.2022.100388
CAS PubMed Google Scholar
98B. Li, G. Huang, Ind. Crops Prod. 2022, 186,115282.
10.1016/j.indcrop.2022.115282
CAS Web of Science® Google Scholar
99S. Zhou, G. Huang, H. Huang, Food Chem. 2022, 388,133000.
10.1016/j.foodchem.2022.133000
CAS PubMed Web of Science® Google Scholar
100Z. Tang, G. Huang, Biomed. Pharmacother. 2022, 150,113015.
10.1016/j.biopha.2022.113015
CAS PubMed Web of Science® Google Scholar
101B. Lin, G. Huang, Biotechnol. Bioeng. 2022, 119(6), 1359–1379.
10.1002/bit.28064
Web of Science® Google Scholar
102Q. Tang, G. Huang, Food Chem. 2022, 376,131937.
10.1016/j.foodchem.2021.131937
CAS Web of Science® Google Scholar
103J. Li, Y. Fan, G. Huang, H. Huang, Ind. Crops Prod. 2022, 178,114675.
10.1016/j.indcrop.2022.114675
Web of Science® Google Scholar
104W. Zhang, G. Huang, J. Sci. Food Agric. 2022, 102, 6193–6201.
10.1002/jsfa.12058
CAS PubMed Web of Science® Google Scholar
105S. Zhou, G. Huang, J. Mol. Struct. 2023, 1273,134379.
10.1016/j.molstruc.2022.134379
CAS Web of Science® Google Scholar
106X. Mei, Q. Tang, G. Huang, R. Long, H. & Huang, Food Chem. 2020, 309, 125791.
10.1016/j.foodchem.2019.125791
CAS PubMed Web of Science® Google Scholar
107G. Benchamas, G. Huang, S. Huang, H. Huang, Trends Food Sci. Technol. 2021, 107, 38–44.
10.1016/j.tifs.2020.11.027
CAS Web of Science® Google Scholar
108F. Chen, G. Huang, H. Huang, Carbohydr. Polym. 2021, 252, 117179.
10.1016/j.carbpol.2020.117179
CAS PubMed Web of Science® Google Scholar
109G. Huang, F. Chen, W. Yang, H. Huang, Trends Food Sci. Technol. 2021, 109, 564–568.
10.1016/j.tifs.2021.01.038
CAS Web of Science® Google Scholar
110W. Yang, G. Huang, Trends Food Sci. Technol. 2021, 112, 50–57.
10.1016/j.tifs.2021.03.025
CAS Web of Science® Google Scholar
111W. Yang, G. Huang, F. Chen, H. Huang, Trends Food Sci. Technol. 2021, 109, 211–218.
10.1016/j.tifs.2021.01.028
CAS Web of Science® Google Scholar
112S. Zhou, G. Huang, Chem. Biol. Technol. Agric. 2023, 10(1), 15.
10.1186/s40538-023-00391-x
CAS Web of Science® Google Scholar
113J. Li, Z. Chen, H. Shi, J. Yu, G. Huang, H. Huang, Ultrason. Sonochem. 2023, 93, 106295.
10.1016/j.ultsonch.2023.106295
CAS PubMed Web of Science® Google Scholar
114Y. Wang, X. Xiong, G. L. Huang, Ultrason. Sonochem. 2023, 95, 106395.
10.1016/j.ultsonch.2023.106395
CAS PubMed Web of Science® Google Scholar
115Y. Fan, G. Huang, Chem. Biodivers. 2023, 20, e202201253.
10.1002/cbdv.202201253
CAS PubMed Web of Science® Google Scholar
116W. Yang, G. L. J. Huang, J. Mol. Struct. 2023, 1285, 135480.
10.1016/j.molstruc.2023.135480
CAS Web of Science® Google Scholar
117R. Ojha, J. Singh, A. Ojha, H. Singh, S. Sharma, K. Nepali, Expert Opin. Ther. Patents 2016, 27, 311–345.
10.1080/13543776.2017.1261111
PubMed Web of Science® Google Scholar
118S. Floris, A. Fais, A. Rosa, A. Piras, H. Marzouki, R. Medda, RSC Adv. 2019, 9, 21278–21287.
10.1039/C9RA02928A
CAS PubMed Web of Science® Google Scholar
119W. El-Tantawy, Arch. Physiol. Biochem. 2019, 1, 1–12.
Google Scholar
120B. Era, G. Delogu, F. Pintus, A. Fais, G. Gatto, E. Uriarte, M. Matos, Int. J. Biol. Macromol. 2020, 162, 774–780.
10.1016/j.ijbiomac.2020.06.152
CAS PubMed Web of Science® Google Scholar

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Volume20, Issue5

May 2023

e202300005

The Inhibitory Activity of Natural Products to Xanthine Oxidase

Abstract

Graphical Abstract

Conflict of interest

References

Citing Literature

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The Inhibitory Activity of Natural Products to Xanthine Oxidase

Abstract

Graphical Abstract

Conflict of interest

References

Citing Literature

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