Article

Preparation and characterization of cyhalothrin-loaded poly(2-hydroxyethyl methacrylate)-co-polylactide (PHEMA-co-PLA) ultrafine particles

Tengfei Fan

College of Science, China Agricultural University, Beijing 100193, People's Republic of China

National Center for Nanoscience and Technology, Laboratory of Nanobiomedicine and Nanosafety, Division of Nanomedicine and Nanobiology, Beijing 100190, People's Republic of China

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Xuemin Wu,

Xuemin Wu

College of Science, China Agricultural University, Beijing 100193, People's Republic of China

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Yan Wu,

Corresponding Author

Yan Wu

[email protected]

National Center for Nanoscience and Technology, Laboratory of Nanobiomedicine and Nanosafety, Division of Nanomedicine and Nanobiology, Beijing 100190, People's Republic of China

National Center for Nanoscience and Technology, Laboratory of Nanobiomedicine and Nanosafety, Division of Nanomedicine and Nanobiology, Beijing 100190, People's Republic of China===Search for more papers by this author

Tengfei Fan,

Tengfei Fan

College of Science, China Agricultural University, Beijing 100193, People's Republic of China

National Center for Nanoscience and Technology, Laboratory of Nanobiomedicine and Nanosafety, Division of Nanomedicine and Nanobiology, Beijing 100190, People's Republic of China

Search for more papers by this author

Xuemin Wu,

Xuemin Wu

College of Science, China Agricultural University, Beijing 100193, People's Republic of China

Search for more papers by this author

Yan Wu,

Corresponding Author

Yan Wu

[email protected]

National Center for Nanoscience and Technology, Laboratory of Nanobiomedicine and Nanosafety, Division of Nanomedicine and Nanobiology, Beijing 100190, People's Republic of China

First published: 24 December 2012

https://doi.org/10.1002/app.38892

Citations: 8

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Abstract

Poly(2-hydroxyethyl methacrylate)-co-polylactide (PHEMA-co-PLA) and its corresponding cyhalothrin-loaded ultrafine particles were successfully synthesized and prepared, respectively. The chemical structures of the copolymers have been confirmed by Fourier transform infrared spectroscopy (FTIR), ¹H-nuclear magnetic resonance (¹H-NMR), ¹³C-nuclear magnetic resonance (¹³C-NMR), and thermogravimetric analysis (TGA). Furthermore, the particle size, the cyhalothrin loading content (LC), and the cyhalothrin release behavior were investigated. PHEMA-co-PLA proved to be a good material for the preparation of ultrafine particles for lipophilic pesticide delivery. The developed cyhalothrin-loaded PHEMA-co-PLA ultrafine particles showed good dispersity in water and sustained release behavior. In addition, it is easy to be prepared by both nanoprecipitation method and emulsion/solvent evaporation method. © 2012 Wiley Periodicals, Inc. J. Appl. Polym. Sci., 2013

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Volume129, Issue4

15 August 2013

Pages 1861-1867

Preparation and characterization of cyhalothrin-loaded poly(2-hydroxyethyl methacrylate)-co-polylactide (PHEMA-co-PLA) ultrafine particles

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Preparation and characterization of cyhalothrin-loaded poly(2-hydroxyethyl methacrylate)-co-polylactide (PHEMA-co-PLA) ultrafine particles

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