Preparation and characterization of silver-chitosan nanocomposite particles with antimicrobial activity
Jing An
School of Sciences, Hebei University of Science and Technology, Hebei, Shijiazhuang 050018, China
School of Materials Science and Engineering, Tianjin Key Laboratory of Composite and Functional Materials, Tianjin University, Tianjin 300072, China
Search for more papers by this authorQingzhi Luo
School of Sciences, Hebei University of Science and Technology, Hebei, Shijiazhuang 050018, China
Search for more papers by this authorXiaoyan Yuan
School of Materials Science and Engineering, Tianjin Key Laboratory of Composite and Functional Materials, Tianjin University, Tianjin 300072, China
Search for more papers by this authorCorresponding Author
Desong Wang
School of Sciences, Hebei University of Science and Technology, Hebei, Shijiazhuang 050018, China
School of Sciences, Hebei University of Science and Technology, Hebei, Shijiazhuang 050018, China===Search for more papers by this authorXueyan Li
School of Sciences, Hebei University of Science and Technology, Hebei, Shijiazhuang 050018, China
Search for more papers by this authorJing An
School of Sciences, Hebei University of Science and Technology, Hebei, Shijiazhuang 050018, China
School of Materials Science and Engineering, Tianjin Key Laboratory of Composite and Functional Materials, Tianjin University, Tianjin 300072, China
Search for more papers by this authorQingzhi Luo
School of Sciences, Hebei University of Science and Technology, Hebei, Shijiazhuang 050018, China
Search for more papers by this authorXiaoyan Yuan
School of Materials Science and Engineering, Tianjin Key Laboratory of Composite and Functional Materials, Tianjin University, Tianjin 300072, China
Search for more papers by this authorCorresponding Author
Desong Wang
School of Sciences, Hebei University of Science and Technology, Hebei, Shijiazhuang 050018, China
School of Sciences, Hebei University of Science and Technology, Hebei, Shijiazhuang 050018, China===Search for more papers by this authorXueyan Li
School of Sciences, Hebei University of Science and Technology, Hebei, Shijiazhuang 050018, China
Search for more papers by this authorAbstract
A nanocomposite of silver nanoparticles (AgNPs) embedded in chitosan (Cts) matrix was successfully synthesized by crosslinking technology. Colloidal AgNPs formed in situ by chemical reduction of silver ions in presence of Cts showed a good stability. Transmission electron micrographs, X-ray diffraction patterns, and UV-visible spectra of Ag-Cts composite particles confirmed the formation of silver nanocrystals. Fourier transform infrared spectroscopy verified the presence of Cts as a stabilizing agent surrounded AgNPs. Thermogravimetric-differential scanning calorimeter analysis revealed Ag-Cts nanocomposite had a higher thermal stability than Cts. X-ray photoelectron spectroscopy suggested that the Ag-O bond in the nanocomposite coule lead to the tight combination between silver and Cts. Microbial experiments showed the nanocomposite had excellent and wide spectrum antibacterial properties, and were more efficient than either AgNPs or Cts alone for inactivating bacteria. Therefore, the resultant nanocomposite could be used as antimicrobial materials for medical and biological applications. © 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2011.
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