Highlight
Hydroxy Functionalization of Non-Activated CH and CC Bonds: New Perspectives for the Synthesis of Alcohols through Biocatalytic Processes†
†
I thank the German Federal Ministry of Education and Research (Bundesministerium für Bildung und Forschung; BMBF) for generous support within the project “BISON—Biotechnologische Synthese von Carboxyaminen und Carboxyalkoholen” (grant number 0316044A).
Graphical Abstract
New perspectives through enzymes: Recent breakthroughs have been achieved in the selective hydroxy functionalization of non-activated CH and CC bonds. Enzymes turned out to be suitable catalysts for the ω-hydroxylation of (substituted) alkanes and regioselective hydroxylation of aromatic hydrocarbons with atmospheric oxygen as the oxidant, and the asymmetric addition of water to non-activated alkenes.
