Enantiopure Water-Soluble [Fe4L6] Cages: Host–Guest Chemistry and Catalytic Activity†
Dr. Jeanne L. Bolliger
Department of Chemistry, University of Cambridge Lensfield Road, Cambridge, CB2 1EW (UK) http://www-jrn.ch.cam.ac.uk
Search for more papers by this authorDr. Ana M. Belenguer
Department of Chemistry, University of Cambridge Lensfield Road, Cambridge, CB2 1EW (UK) http://www-jrn.ch.cam.ac.uk
Search for more papers by this authorCorresponding Author
Dr. Jonathan R. Nitschke
Department of Chemistry, University of Cambridge Lensfield Road, Cambridge, CB2 1EW (UK) http://www-jrn.ch.cam.ac.uk
Department of Chemistry, University of Cambridge Lensfield Road, Cambridge, CB2 1EW (UK) http://www-jrn.ch.cam.ac.ukSearch for more papers by this authorDr. Jeanne L. Bolliger
Department of Chemistry, University of Cambridge Lensfield Road, Cambridge, CB2 1EW (UK) http://www-jrn.ch.cam.ac.uk
Search for more papers by this authorDr. Ana M. Belenguer
Department of Chemistry, University of Cambridge Lensfield Road, Cambridge, CB2 1EW (UK) http://www-jrn.ch.cam.ac.uk
Search for more papers by this authorCorresponding Author
Dr. Jonathan R. Nitschke
Department of Chemistry, University of Cambridge Lensfield Road, Cambridge, CB2 1EW (UK) http://www-jrn.ch.cam.ac.uk
Department of Chemistry, University of Cambridge Lensfield Road, Cambridge, CB2 1EW (UK) http://www-jrn.ch.cam.ac.ukSearch for more papers by this authorThis work was supported by the Swiss National Science Foundation (SNSF) and the European Research Council. We thank the EPSRC Mass Spectrometry Service at Swansea for conducting FT-ICR MS experiments.
Graphical Abstract
Inside information: The new enantiopure cage molecule ΔΔΔΔ-Fe4L6 (and its enantiomer, ΛΛΛΛ-Fe4L6) was prepared by subcomponent self-assembly. It binds a range of organic guests (A, see scheme) in its cavity and distinguishes between the enantiomers of a chiral organic guest. Host ΔΔΔΔ-Fe4L6 is also a catalyst for the hydrolysis (giving B and C) of the neurotoxic organophosphate dichlorvos.
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