Self-Assembled Organic Nanostructures with Metallic-Like Stiffness†
Lihi Adler-Abramovich
Department of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978 (Israel)
These authors contributed equally to this work.
Search for more papers by this authorNitzan Kol
Department of Structural Biology, Weizmann Institute of Science, Rehovot 76100 (Israel)
These authors contributed equally to this work.
Search for more papers by this authorInbal Yanai
Department of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978 (Israel)
Search for more papers by this authorProf. David Barlam
Department of Mechanical Engineering, Ben-Gurion University of the Negev (Israel)
Search for more papers by this authorProf. Roni Z. Shneck
Department of Materials Engineering, Ben-Gurion University of the Negev (Israel)
Search for more papers by this authorCorresponding Author
Prof. Ehud Gazit
Department of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978 (Israel)
Ehud Gazit, Department of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978 (Israel)
Itay Rousso, Department of Structural Biology, Weizmann Institute of Science, Rehovot 76100 (Israel)
Search for more papers by this authorCorresponding Author
Prof. Itay Rousso
Department of Structural Biology, Weizmann Institute of Science, Rehovot 76100 (Israel)
Ehud Gazit, Department of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978 (Israel)
Itay Rousso, Department of Structural Biology, Weizmann Institute of Science, Rehovot 76100 (Israel)
Search for more papers by this authorLihi Adler-Abramovich
Department of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978 (Israel)
These authors contributed equally to this work.
Search for more papers by this authorNitzan Kol
Department of Structural Biology, Weizmann Institute of Science, Rehovot 76100 (Israel)
These authors contributed equally to this work.
Search for more papers by this authorInbal Yanai
Department of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978 (Israel)
Search for more papers by this authorProf. David Barlam
Department of Mechanical Engineering, Ben-Gurion University of the Negev (Israel)
Search for more papers by this authorProf. Roni Z. Shneck
Department of Materials Engineering, Ben-Gurion University of the Negev (Israel)
Search for more papers by this authorCorresponding Author
Prof. Ehud Gazit
Department of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978 (Israel)
Ehud Gazit, Department of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978 (Israel)
Itay Rousso, Department of Structural Biology, Weizmann Institute of Science, Rehovot 76100 (Israel)
Search for more papers by this authorCorresponding Author
Prof. Itay Rousso
Department of Structural Biology, Weizmann Institute of Science, Rehovot 76100 (Israel)
Ehud Gazit, Department of Molecular Microbiology and Biotechnology, George S. Wise Faculty of Life Sciences, Tel Aviv University, Tel Aviv 69978 (Israel)
Itay Rousso, Department of Structural Biology, Weizmann Institute of Science, Rehovot 76100 (Israel)
Search for more papers by this authorWe thank Dr. Ellen Wachtel for help with the XRD analysis, Prof. Yeshayahu Talmon for help with the ED analysis, Dr. Zahava Barkay for help with the SEM analysis, Prof. Reshef Tenne and Ofer Tevet for the use of the HR-SEM equipped with nanomanipulator, and members of the Gazit laboratory for helpful discussions. L.A.A. gratefully acknowledges the support of the Colton Foundation. I.R. holds the Robert Edwards and Roselyn Rich Manson Career Development Chair. We thank the Israel Science Foundation for financial support.
Graphical Abstract
Stiff spheres: AFM experiments using a diamond-tip cantilever show that aromatic dipeptide nanospheres (see picture) have a remarkable metallic-like Young's modulus of up to 275 GPa. This exceptional value places these nanostructures as the stiffest organic materials reported to date, thus making them attractive building blocks for the design and assembly of ultrarigid composite biomaterials.
Supporting Information
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