The Molecular Basis of Eukaryotic Transcription (Nobel Lecture)†
Copyright© The Nobel Foundation 2006. We thank the Nobel Foundation, Stockholm, for permission to print this lecture.
Graphical Abstract
Life under the microscope: Transcription, the copying of a DNA strand to produce an RNA strand, is a central operation in biology. The complex mechanism of eukaryotic transcription has been broken down into molecular details through the work of Roger Kornberg.The Nobel Prize winner for Chemistry describes here first hand the course of his research. The picture shows the pre-initiation complex that must be formed for initiation of transcription.
Abstract
I am deeply grateful for the honor bestowed on me by the Nobel Committee for Chemistry and the Royal Swedish Academy of Sciences. It is an honor I share with my collaborators. It is also recognition of the many who have contributed over the past quarter century to the study of transcription.
