Volume 46, Issue 32 pp. 6089-6092
Communication

Functional DNA Nanotube Arrays: Bottom-Up Meets Top-Down

Chenxiang Lin

Chenxiang Lin

Department of Chemistry and the Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA, Fax: (+1) 480-727-2378

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Yonggang Ke

Yonggang Ke

Department of Chemistry and the Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA, Fax: (+1) 480-727-2378

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Yan Liu Dr.

Yan Liu Dr.

Department of Chemistry and the Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA, Fax: (+1) 480-727-2378

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Michael Mertig Prof.

Michael Mertig Prof.

Arbeitsgruppe Bionanotechnologie und Strukturbildung, Max-Bergmann-Zentrum für Biomaterialien, Technische Universität Dresden, 01062 Dresden, Germany

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Jian Gu Dr.

Jian Gu Dr.

Department of Chemistry and the Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA, Fax: (+1) 480-727-2378

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Hao Yan Prof. Dr.

Hao Yan Prof. Dr.

Department of Chemistry and the Biodesign Institute, Arizona State University, Tempe, AZ 85287, USA, Fax: (+1) 480-727-2378

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First published: 03 August 2007
Citations: 61

This research was partly supported by grants from the NSF, the NIH, AFOSR, ONR, and Arizona State University to H.Y. M.M. acknowledges support from the DFG (ME1256/9-1).

Graphical Abstract

Meeting in the middle: Well-organized arrays of self-assembled functional DNA nanotubes can be constructed by combining bottom-up and top-down methods. Such DNA-nanotube arrays allow the construction of arrays of quantum dots, proteins, and DNA targets (see picture; green: DNA nanotube, red: streptavidin–quantum dot conjugate; scale bar: 20 μm).

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