Volume 119, Issue 8 pp. 1340-1342
Zuschrift

Patterned Paper as a Platform for Inexpensive, Low-Volume, Portable Bioassays

Andres W. Martinez

Andres W. Martinez

Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA, Fax: (+1) 617-495-9857

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Scott T. Phillips Dr.

Scott T. Phillips Dr.

Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA, Fax: (+1) 617-495-9857

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Manish J. Butte Dr.

Manish J. Butte Dr.

Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA, Fax: (+1) 617-495-9857

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George M. Whitesides Prof.

George M. Whitesides Prof.

Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA, Fax: (+1) 617-495-9857

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First published: 05 February 2007
Citations: 360

This research was supported by the National Institutes of Health (NIH) (GM065364). We used the Materials Research Science and Engineering Centers (MRSEC) shared facilities supported by the National Science Foundation (NSF) under award number DMR-0213805. This work also was supported by a predoctoral fellowship from NSF (A.W.M), a Damon Runyon Cancer Research Foundation Fellowship (DRG-1805-04) (S.T.P), and an Alexander and Margaret Stewart Trust Award and Massachusetts Technology Transfer Council Grant (M.J.B.).

Graphical Abstract

Einfach überzeugend: Ein Verfahren zur Mustererzeugung auf Papier mit einem Fotolack liefert definierte, millimetergroße Kanäle aus hydrophilem Papier und hydrophobem Polymer. Diese Art von bedrucktem Papier ist ein Prototyp billiger, transportabler und technisch einfacher Plattformen für gebündelte Bioassays mit Mikrolitervolumina einer einzelnen biologischen Probe.

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